Haemoglobin present in human blood binds to oxygen in which oxidation state?
A
Fe2+
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B
Fe3+
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C
Fe4+
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D
Fe+
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Solution
The correct option is DFe2+ Haemoglobin is the iron-containing oxygen-transport metalloprotein in the red blood cells. The iron ion, which is the site of oxygen binding, coordinates with the four nitrogen atoms in the center of the ring.
The iron ion may be either in the Fe2+ or in the Fe3+ state, but ferrihemoglobin (methemoglobin) (Fe3+) cannot bind oxygen. Iron must exist in the +2 oxidation state to bind oxygen.