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Question

Haemophilia is a sex-linked recessive disease. Study the pedigree analysis given showing the inheritance of the disease in a family and answer the question that follows.
Write the possible genotype of the individual '2' and '5'.
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Solution

Haemophilia is a sex-linked recessive disease. The female '2' is heterozygote or carrier for the disease so she does not express the disease herself. The genotype of '2' is thus XhX. The male in the F1 generation,i.e. '5' is a victim male of the disease so it has the genotype of XhY.

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