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B
Non-random mating
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C
Genetic drift
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D
All of the above
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Solution
The correct option is D All of the above
The conditions to maintain the Hardy-Weinberg equilibrium are no mutation, no gene flow, large population size, random mating, and no natural selection.
Hardy-Weinberg equilibrium is disturbed by deviation from any of its five conditions.
Hence, Hardy-Weinberg equilibrium can be disturbed by Mutations, Non-random mating and Genetic drift.