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Inheritance of Haemophilia

Heamophilia i...

Question

Heamophilia is more commonly seen in human males than in human females because

A

a greater proportion of girls die in infancy

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B

this disease is due to a Y-linked recessive mutation

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C

This disease is due to an X – linked recessive mutation

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D

this disease is due to an X – linked dominant mutation

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Solution

The correct option is C This disease is due to an X – linked recessive mutation
Heamophilia is more commonly seen in human males than in human females because this disease is due to an X – linked recessive mutation.

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Q. Assertion :Haemophilia is a recessive sex linked disease. Reason: Haemophilia occurs due to mutation of a structural gene on chromosome 15.

Q. Pick out the correct statements:
(i) Hemophilia is a sex – linked recessive disease
(ii) Down’s syndrome is due to aneuploidy
(iii) Phenylketonuria is an autosomal recessive gene disorder
(iv) Sickle cell anaemia is an X-linked recessive gene disorder

Pick out the correct statements.

(i) Haemophilia is a sex-linked recessive disease.

(ii) Down's syndrome is due to aneuploidy.

(iii) Phenylketonuria is an autosomal dominant gene disorder.

(iv) Phenylketonuria is an autosomal recessive gene disorder.

(v) Sickle-cell anaemia is an X-linked recessive gene disorder.

Q. Duchenne muscular dystrophy is a lethal X-linked recessive disease which affects 1 in 3,500 boys.
What is the frequency of carriers of this gene mutation in females?

________ linked diseases are mainly due to recessive genes present on the X-chromosome.

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Inheritance of Haemophilia

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