Question

Hinge region in antibodies is important because it

• A. Provides flexibility to the antibody molecules
• B. Helps change the shape of antibody
• C. Helps in binding of antibody to pathogens
• D. Prevents the antibody from degradation

Answer 1

Answer: (A), (B)

The correct options are
A

Provides flexibility to the antibody molecules

B

Helps change the shape of antibody

The antibody molecule is made up of two heavy and two light chains. A small hinge region is present between the constant region one and constant region two of the antibody molecule. This hinge region provides flexibility to the molecule and allows the molecule to change shape which is helpful in binding to antigens of different shapes and sizes.