Question

Holoenzyme is the complete enzyme consisting of an apoenzyme and a co-factor. Select the option that correctly identifies the nature of apoenzyme and co-factor.

• A. Apoenzyme - Protein
  Co - factor - Non-Protein
• B. Apoenzyme - Non - Protein
  Co - factor - Protein
• C. Apoenzyme - Protein
  Co - factor - Protein
• D. None of the above
  

Answer 1

Answer: (A)

Apoenzyme - Protein

Co - factor - Non-Protein
Conjugated enzymes ( holoenzymes) are formed of two parts a protein part called apoenzyme and a non-protein part named co-factor. The complete conjugated enzyme consisting of an apoenzyme and a co-factor is called holoenzyme. Holoenzyme is the functional unit of enzyme.

$\underset{\left(activeenzyme\right)}{Holoenzyme}$ $\to$ $\underset{\left(proteinpart\right)}{Apoenzyme}$ $+co-factor$

Co-factor may be inorganic or organic in nature. Catalystic activity is lost when co-factor is removed from the enzyme which indicates that it plays a crucial role in catalytic activity of enzymes.

So, the correct answer is 'Apoenzyme - Protein, Co - factor - Non-Protein'.