Calcitonin or thyrocalcitonin is a polypeptide hormone produced by the parafollicular cells or the c-cells present in thyroid. This hormone is responsible for regulation of blood calcium and phosphorus. It results in generation of opposite effects of parathyroid hormone. Main effect of calcitonin is to reduce the blood calcium level in blood by inhibiting the bones’ osteoclastic activity, stimulation of osteoblastic activity in bones and promotes excretion of calcium in the urine.