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Question

Hormones from the hypothalamus affect the release of all of the following except

A
Prolactin
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B
Oxytocin
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C
Thyroid stimulating hormone
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D
Growth hormone
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Solution

The correct option is B Oxytocin
The anterior pituitary gland, unlike the posterior pituitary, is not derived from the brain and does not receive an axon tract from the hypothalamus. The hypothalamus controls the production and secretion of the anterior pituitary hormones with the help of hormones. Neurons in the hypothalamus secrete releasing hormones and inhibiting hormones which regulate the secretion of specific anterior pituitary hormones. Prolactin, TSH, and GH are all anterior pituitary hormones.
Whereas Oxytocin and vasopressin, two peptide hormones, are actually synthesized in the hypothalamus and then transported axonally to the posterior pituitary gland. So, hypothalamus does not produce any releasing hormone for pituitary to release oxytocin. It itself releases the hormone.

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