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Question

Hormones secreted by the placenta to maintain pregnancy are:

A
hCG, hPL, progestogens, estrogens
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B
hCG, hPL, estrogens, relaxin, oxytocin
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C
hCG, hPL, progestogens, prolactin
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D
hCG, progestogens, estrogens, glucocorticoids
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Solution

The correct option is A hCG, hPL, progestogens, estrogens
The placenta is an organ that develops in the uterus during pregnancy. This structure provides oxygen and nutrients to the developing embryo and removes excretory wastes. It is connected to the embryo through an umbilical cord which helps in the transport of substances.

Placenta is also an endocrine tissue and produces hormones.

The placenta produces two steroid hormones – estrogens, progestogens. Progestogens prevent the shedding of the endometrial lining, since this would result in abortion. Estrogen acts to stimulate the growth of the endometrium in order to accommodate the growing foetus.

The placenta also releases several other hormones, which include human chorionic gonadotropin (hCG) and human placental lactogen (hPL).

Relaxin hormone is secreted during the later phase of pregnancy by the corpus luteum of the ovary. It relaxes the ligaments in the pelvis and softens and widens the cervix and thus helps in childbirth.

Oxytocin is normally produced in the hypothalamus but stored and released by the posterior pituitary. It stimulates uterine contractions and facilitates childbirth.

Prolactin regulates the growth of mammary glands and secretion of milk in them. It is secreted by the anterior pituitary.

Glucocorticoids regulate carbohydrate metabolism and they are secreted by the adrenal cortex.

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