In a given species, chromosomes can be identified by their number, size, centromere position, and banding pattern. In a human karyotype, autosomes or "body chromosomes" (all of the non-sex chromosomes) are generally organized in approximate order of size from largest (chromosome 1) to smallest (chromosome 22). However chromosome 21 is actually shorter than chromosome 22. This was discovered after the naming of Down syndrome as trisomy 21, reflecting how this disease results from possessing one extra chromosome 21 (three total). Not wanting to change the name of this important disease, chromosome 21 retained its numbering, despite describing the shortest set of chromosomes. The X and Y chromosomes are not autosomes and are referred to as the sex chromosomes. The chromosome "arms" projecting from either end of the centromere may be designated as short or long, depending on their relative lengths. The short arm is abbreviated p (for "petite"), whereas the long arm is abbreviated q (because it follows "p" alphabetically).