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Question

How can proteins survive at temperatures as high as 100 degree celsius in a living system?

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Solution

The melting temperature varies for different proteins, but temperatures above 41C(105.8F) will break the interactions in many proteins and denature them. This temperature is not that much higher than normal body temperature (37C or 98.6F), so this fact demonstrates how dangerous a high fever can be.
Ahyperthermophileis an organism that thrives in extremely hot environments - from 60C(140F) upwards. An optimal temperature for the existence of hyperthermophiles is above 80C(176F). Hyperthermophiles are a subset of extremophiles, micro-organisms within the domain Archaea, although some bacteriaare able to tolerate temperatures of around 100C(212F), as well. Some bacteria can live at temperatures higher than 100C at large depths in sea where water does not boil because of high pressure.
So the conclusion will be, in the organisms which survive at 37C or 98.6F, their proteins will get denatured above 41C(105.8F) except hyperthermophiles which can tolerate high temperatures.

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