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B
By crossing them with their wild relatives
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C
Destroying diseased ones
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D
Eliminating wild species
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Solution
The correct option is D By crossing them with their wild relatives Our crops could be made disease resistant by crossing them with wild varieties, which has disease resistance gene. This helps in yielding a new breed, which is highly disease resistant as well as carries the features of the existing variety.
So, the correct answer is 'By crossing them with their wild relatives'