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How did we come to know about germ layers?

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A germ layer is a group of cells in an embryo that interact with each other as the embryo develops and contribute to the formation of all organs and tissues. All animals, except perhaps sponges, form two or three germ layers. The germ layers develop early in embryonic life, through the process of gastrulation. During gastrulation, a hollow cluster of cells called a blastula reorganizes into two primary germ layers: an inner layer, called endoderm, and an outer layer, called ectoderrm Diploblastic organisms have only the two primary germ layers these organisms characteristically have multiple symmetrical body axes (radial symmetry), as is true of jellyfish, sea anemones, and the rest of the phylum Cnidaria All other animals are triploblastic, as endoderm and ectoderm interact to produce a third germ layer, called mesoderrm Together, the three germ layers will give rise to every organ in the body, from skin and hair to the digestive tract.

Caspar Friedrich Wolff observed organization of the early embryo in leaf-like layers. In 1817, Heinz Christian Pander discovered three primordial germ layers while studying chick embryos. Between 1850 and 1855,Robert Remark had further refined the germ cell layer (Keimblatt) concept, stating that the external, internal and middle layers form respectively the epidermis, the gut, and the intervening musculature and vasculature.

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