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Question

How do prions kill brain cells?


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Solution

Prions

  1. They are said to be virus-like organisms made up of a prion protein.
  2. They have elongated fibrils that are said to be aggregations of the protein that makes them infectious prion.
  3. Prions attacks nerve cell fibers producing neurodegenerative brain disease.
  4. "Mad cow" symptoms include glazed eyes and uncontrollable body tremors caused by prions.
  5. Yes, prions kill brain cells.
  6. The infectious proteins or prions can cause the other proteins to fold abnormally.
  7. The abnormally folded proteins get accumulated in the brain which damages to the dendrites and can result in memory impairment, personality changes, and difficulties with movement.

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