How do receptor tyrosine kinases work?

Open in App

Solution

Receptor tyrosine kinases are cell surface receptors with intrinsic enzymatic activity. It is a part of the protein receptor. These kinases are involved in signalling pathways which activate RTK that are soluble in protein or membrane-bound hormones, growth factors, and cytokines. These kinases undergo receptor dimerization and autophosphorylation
Receptor tyrosine kinases regulate differentiation, cellular metabolism, cell survival and proliferation.
Tyrosine kinases catalyze the transfer of phosphate group from ATP to tyrosine. These don't involve G-proteins.
These are the key regulators of normal cellular processes but also have a critical role in the development and progression of many diseases.
These kinases are involved in mediating cell-to-cell communication and controlling a wide range of complex biological functions. Examples: Epidermal growth factor receptors, Platelet-derived growth factor receptors, ROS1, RET.

Suggest Corrections

Similar questions

How do stomata open and close? Do they use receptor?

what is the function of receptors in human body? what are the types of receptors found in humans? what problems are likely to occur if receptors do not work properly?

What is the function of receptors in our body? Think of a situation where receptors do not work properly. what problems are likely to arise. explain.

Question 4
What is the function of receptors in our body? Think of situations where receptors do not work properly. What problems are likely to arise?

Q. State the function of receptors in our body. Think of any three situations where receptors in the body do not work properly. Mention the problems which are likely to arise.

Join BYJU'S Learning Program