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Question

How do you apply the Hardy Weinberg Equation?


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Solution

Hardy Weinberg Equation:

  1. The Hardy Weinberg equation refers to the calculation of the genetic variation of a population at an equilibrium state.
  2. The equation is expressed as, p2 + 2pq + q2 = 1
  3. Let's suppose a height-determining gene is expressed by two alleles ‘L’ and ‘l’, where p is the frequency of the “L” allele and q is the frequency of the ‘l'' allele.
  4. p2 represents homozygous genotype “LL”
  5. q2 represents homozygous genotype ‘ll’
  6. The pq in the equation represents heterozygous genotype Ll.
  7. According to the equation, p+q=1.
  8. If the allele frequencies are known, then the gene frequencies can be calculated from the equation if there is no mutation, gene flow, random mating, and selection occurred. It is just a theoretical approach to predicting gene frequency.

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