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Question

How do you find the frequency of a recessive allele?


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Solution

Frequency of a recessive allele:

  1. A recessive allele is a form of genetic coding that does not produce a phenotype in the presence of a dominant allele.
  2. To compute the frequency of recessive alleles, use the Hardy-Weinberg equilibrium equation.
  3. The recessive allele's frequency is denoted by q, and it can be computed by taking the square root of q2.
  4. The frequency of homozygotes for the recessive allele, which shows a recessive phenotype and can be easily quantified in a population, is denoted by q2.

Hardy-Weinberg equilibrium equation:

p^2 + 2pq + q^2 = 1

where,

p2 = dominant homozygous frequency

2pq = heterozygous frequency

q2 = recessive homozygous frequency


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