Question

How does a chromosomal disorder differ from a Mandelson disorder?

Answer 1

Solution:

Some of the major difference between chromosomal and mendelian disorders are as follows:

Chromosomal Disorders:

1. The disorders are caused by chromosomal abnormalities.

2. Chromosomal abnormalities develop due to defective synapsis and disjunction.

3. The defect can be known through amniocentesis.

4. The disorder is rarely transmitted.

Mendelian Disorders:

1. The disorders are caused by allelic abnormalities.

2. Allelic abnormalities develop due to mutations.

3. The defect can be predicted through pedigree analysis.

4. The disorder is transmitted to the progeny.

(Answer)