Binary Fission | Multiple Fission |
It occurs during favorable condition | It occurs during unfavorable condition |
The parent cell divides first through karyokinesis followed by cytokinesis and two daughter cells are produced. | The parent cell divides continuously through karyokinesis and cytokinesis does not occur immediately. Many daughter nuclei are formed in the parent cell. |
There is no cyst formation. | The parent cell forms the cyst to protect the daughter nuclei, which is broken when the favorable conditions return. |