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Question

How is the repressor different from the corepressor?


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Solution

Repressor: It is a protein that attaches directly to DNA or RNA and prevents one or more genes from being expressed.

Corepressors: These are special transcriptional protein regulators that help to regulate repressors without binding to DNA.

RepressorCorepressor
  1. These repressor proteins frequently bind with the promoter region or associated silencers.
  1. A corepressor is a protein that binds to the repressor protein and can activate repressors.
2. Repressor proteins directly attach to the operator sequence of the gene and limit gene expression. 2. Corepressor proteins bind to repressor proteins and indirectly control gene expression.
3. Repressor prevents RNA polymerase from attaching to the promoter. 3. Corepressor competes with coactivators to bind transcription factors.
4. Repressors can be activated by corepressors, a protein that binds to the repressor protein. 4. Corepressors are proteins themselves that bind to repressor proteins.
5. Repressor proteins directly attach to the operator sequence of the gene and limit gene expression. 5. Corepressor proteins bind to repressor proteins and indirectly control gene expression.
6. Repressor prevents RNA polymerase from attaching to the promoter. 6. Corepressor competes with coactivators to bind transcription factors.

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