How is vaccine produced
How is vaccine produced
Vaccines are made using the disease-causing virus or bacteria, but in a form that will not harm .
Once it is determined how the virus and bacteria will be modified, vaccines are created through a general three-step process:
1. Antigen is generated. Viruses are grown in primary cells (i.e. chicken eggs for the influenza vaccine), or on continuous cell lines (i.e. human cultured cells for hepatitis b vaccine); bacteria is grown in bioreactors (i.e. Hib vaccine).
2. Antigen is isolated from the cells used to create it.
3. Vaccine is made by adding adjuvant, stabilizers and preservatives. Adjuvants increase immune response of the antigen; stabilizers increase the vaccine’s storage life; and preservatives allow for the use of multi-dose vials.
Vaccines are made using the disease-causing virus or bacteria, but in a form that will not harm .
Once it is determined how the virus and bacteria will be modified, vaccines are created through a general three-step process:
1. Antigen is generated. Viruses are grown in primary cells (i.e. chicken eggs for the influenza vaccine), or on continuous cell lines (i.e. human cultured cells for hepatitis b vaccine); bacteria is grown in bioreactors (i.e. Hib vaccine).
2. Antigen is isolated from the cells used to create it.
3. Vaccine is made by adding adjuvant, stabilizers and preservatives. Adjuvants increase immune response of the antigen; stabilizers increase the vaccine’s storage life; and preservatives allow for the use of multi-dose vials.
