The name refers to a sequence of reactions in which oxygen is required to reoxidize NADH to NAD+. This ten-step procedure starts with a molecule of glucose and concludes with two pyruvate molecules.
Glycolysis is critical for the brain's energy needs, which are met by glucose.
In tissues without mitochondria, such as erythrocytes, cornea, and lenses, glycolysis is a critical mechanism for ATP generation.
Pyruvate enters the citric acid cycle under aerobic conditions and undergoes oxidative phosphorylation, yielding 32 ATP molecules.