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Question

How many ATP does acetyl CoA produce?


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Solution

Acetyl CoA:

  1. The tricarboxylic acid (TCA) cycle, commonly known as the Krebs or citric acid cycle, is the primary source of energy for cells and is an essential component of aerobic respiration.
  2. The cycle converts acetyl coenzyme A's (acetyl CoA) chemical energy into nicotinamide adenine dinucleotide's reducing power (NADH).
  3. During glycolysis, two molecules of pyruvates are produced.
  4. These two pyruvates combine to form two molecules of acetyl CoA, which are then recycled into the Krebs cycle.
  5. When isocitrate is converted to oxalosuccinate, NADH is produced.
  6. When ketoglutarate is converted to succinyl-CoA, one NADH is produced.
  7. When succinyl CoA is converted to succinic acid, 1 GTP is generated.
  8. When succinic acid is converted to fumaric acid, FADH2 is generated.
  9. When malate is converted to oxaloacetate, NADH is produced.1NADH+1NADH+1GTP+1FADH2+1NADH=3+3+1+2+3=12ATP

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