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Question

How many molecules of carbon dioxide are released in Krebs cycle per glucose molecule?

A
2
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B
3
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C
4
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D
6
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Solution

The correct option is C 4
Krebs cycle, also known as the TCA (tricarboxylic acid) or citric acid cycle, takes place inside the mitochondrial matrix. This cycle is a stepwise oxidative and cyclic degradation of acetyl CoA. The cycle acts on the 2 pyruvate molecules generated during glycolysis.

The end product of glycolysis is pyruvate. 1 molecule of glucose produces 2 molecules of pyruvate. So 1 molecule of pyruvate is responsible for the release of 2 CO2 molecules during 1 Krebs cycle. Since 1 glucose molecule gives 2 pyruvate molecules. There will be two cycles to utilize both the pyruvate molecules. Thus, 1 glucose molecule is responsible for the release of 4 CO2 molecules during Krebs cycle.


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