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Question

How many molecules of CO2 are released in citric acid cycle :-

A
One
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B
Two
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C
Three
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D
Four
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Solution

The correct option is D Four
Citric acid cycle is also called as Tricarboxylic acid cycle or Krebs cycle. Acetyl CoA enters a cyclic pathway known as citric acid cycle. There are two molecules produced for every molecule of pyruvate in the citric acid cycle. They are produced by decarboxylation reactions. The first decarboxylation produces alpha ketoglutarate from oxalosuccinate in a reaction catalysed by isocitrate dehydrogenase. The second produces succinyl CoA from alpha ketoglutarate in a reaction catalysed by alpha ketoglutarate dehydrogenase. Therefore, total two molecules of carbon dioxide are released in citric acid cycle.
So, the correct option is 'four'.

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