Question

How many statements are correct regarding Rheumatoid arthritis?

(a) Caused due to activation of Rheumatic factor IgG type antibody
(b) Synovial joints are affected
(c) Pannus particles are formed by articular cartilage
(d) Rheumatic factor is activated by recurrent E.coli infection
(e) Articular cartilage is damaged by pannus particles.

• A. One
• B. Two
• C. Three
• D. Four

Answer 1

The correct option is C Three

Answer is C. Three

A In rheumatoid arthritis an antibody against the Fc portion of IgG and different RFs can recognize different parts of the IgG-Fc. RF and IgG join to form immune complexes that contribute to the disease process.

B. The synovial membrane produces synovial fluid – a clear fluid that lubricates and nourishes the joint. Rheumatoid arthritis can affect any joint in the body but usually affects the small joints in the hands and feet before any of the larger joints such as hips, knees, shoulders and elbows are affected.

E.pannus — an abnormal tissue growth in the joints. This tissue can spread to your bones and cartilage, causing cartilage destruction, bone deterioration, pain, and inflammation.