Question

How many statements regarding male contraception are correct?
i. Male pills come with the formulation of Dimethandrolone undecanoate (DMAU) that inhibits spermatogenesis
ii. DMAU inhibits the pituitary from releasing LH, but not FSH
iii. Male contraceptive pills can cause reduced sex drive, weight gain and tiredness
iv. Gossypol helps in increasing sperm production

• A. 2
• B. 3
• C. 1
• D. 4

Answer 1

The correct option is A 2

Contraception is the most acceptable route for checking population explosion in the world. Traditionally, it was focused on women, but using both hormonal and non-hormonal contraception methods for males can be an attractive alternative.
Male pills are formulated by using the chemical Dimethandrolone undecanoate (DMAU) which inhibits the pituitary gland from producing both follicle-stimulating hormones (FSH) and luteinising hormones (LH). FSH and LH control the process of spermatogenesis.
Male contraception pills ultimately lead to low testosterone production from the testes which causes mild erectile dysfunction, reduced sex drive and tiredness.
Gossypol is an extract from the cotton plant and it has been studied for use as male contraception pill. It decreases sperm production. It acts as a contraceptive by inhibiting enzyme systems that affect energy metabolism in sperm and spermatogenic cells.