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Question

How to compare the acidic strength by inductive and mesomeric effect?

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Solution

The mesomeric effect is given priority over Inductive effect when both effects come into play.

Inductive:
More -I (Negative inductive effect) - more acidic
More+I (Positive inductive effect) - less acidic

Mesomeric:
More -M or -R - more acidic.
More+M or +R - less acidic.

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