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Question

Human fetal haemoglobin differs from the adult haemoglobin in that it has

A
Higher affinity for oxygen.
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B
Lower affinity for oxygen.
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C
Two subunits only.
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D
Is glycosylated.
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Solution

The correct option is A Higher affinity for oxygen.
Fetal haemoglobin has two alpha and two gamma subunit whereas adult haemoglobin has two alpha and two beta subunits. Fetal haemoglobin has a great affinity for oxygen because of its interaction with 2,3-bisphosphoglycerate and thus, shows oxy-haemoglobin dissociation curve towards left. Thus, the correct answer is option A.

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