Question

Hypersecretion of growth hormone by pituitary results in

• A. Dwarfism
• B. Gigantism
• C. Cretinism
• D. Myxedema

Answer 1

Answer: (B)

Gigantism

a) GH is the growth hormone, secreted by the anterior pituitary, which targets soft tissues and bones and serves to stimulate cell division, protein synthesis and bone growth. Dwarfism is caused by underproduction of GH in childhood and is characterized by perfect proportions but small stature.

b) Overproduction of GH in childhood and adolescence causes gigantism which is characterized by excessive growth and poor health as a secondary effect.

c) Cretinism is caused by the underdeveloped thyroid gland and is characterized by short and stocky stature due to hypothyroidism since infancy or childhood.

d) Myxedema is caused by hypothyroidism in adults and is characterized by lethargy, hair loss, weight gain, puffed skin, lowered body temperature and slowed pulse rate.

So, the correct answer is option B.