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Question

Identify A and B in the given reaction.
Pyruvicacid+CoA+NAD+Mg2+−−−−−−−−−−−−−−−→PyruvatedehydrogenaseA+B+NADH+H+

A
A- PEP ; B-CO2
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B
A-Acetyl CoA ; B-CO2
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C
A-CO2 ; B- H2O
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D
A- Acetyl CoA ; B-H2O
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Solution

The correct option is D A-Acetyl CoA ; B-CO2

During aerobic respiration, pyruvic acid which is formed during glycolysis enters mitochondrial matrix. It undergoes oxidative decarboxylation to produce CO2 and NADH. The product combines with sulfur-containing co-enzyme A to form acetyl CoA. This reaction is catalyzed by an enzyme complex pyruvate dehydrogenase. This step is called link reaction or gateway step as it links glycolysis with Krebs' cycle.
Pyruvicacid+COA+NAD+Mg2+−−−−−−−−−−−−−−PyruvatedehydrogenaseAcetylCoA+CO2+NADH+H+
So the correct answer is 'A-Acetyl CoA ; B-CO2'.

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