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Question

Identify the components labelled (A-D) in the given flow chart of the blood clotting process.
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A
A - Thromboplastin, B - Prothrombinase, C - Thrombin, D - Fibrinogen
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B
A -Fibrinogen, B - Thrombin, C - Prothrombinase, D - Thromboplastin
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C
A -Prothrombinase, B - Fibrinogen, C - Thromboplastin, D - Thrombin
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D
A -Thrombin, B - Thromboplastin, C - Fibrinogen, D - Prothrombinase
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Solution

The correct option is A A - Thromboplastin, B - Prothrombinase, C - Thrombin, D - Fibrinogen

Option A. A - Thromboplastin, B - Prothrombinase, C - Thrombin, D – Fibrinogen

Reason: In the following diagram, the process of blood clotting. In the first step at the site of an injury, the blood platelets disintegrate and release a phospholipid, called platelet factor-3. Injured tissues also release a lipoprotein factor called thromboplastin. These two factors combine with calcium ions and certain proteins of blood plasma to form an enzyme called prothrombinase. In the second step, prothrombinase inactivates heparin in the presence of calcium. Prothrombinase catalyzes the breakdown of prothrombin into an active protein called thrombin. In the third step, thrombin acts as an enzyme and first brings about depolymerization of fibrinogen into its monomers. Later thrombin stimulates repolymerization of these monomers into long insoluble fiber-like polymers called fibrin.


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