Question

Identify the DNA segment that is not a palindromic sequence

• A. 5' GAATTC 3' 3' CTTAAG 5'
  
• B. 5' CCCGGG 3' 3' GGGCCC 5'
• C. 5' GGATCC 3' 3' GGTACC 5'
• D. 5' GCGGCCGC 3' 3' CGCCGGCG 5'

Answer 1

The correct option is C 5' GGATCC 3' 3' GGTACC 5'

A palindromic sequence is a nucleic acid sequence that is the same whether read from 5'-3' direction on the strand or 3'-5' direction on the complementary strand of which each forms a double helix. They are basically inverted repeats of nucleotides on dsDNA or the restriction sites of restriction endonucleases.
5' GGATCC 3' is not palindromic to 3' GGTACC 5'.