Question

Identify the most acidic hydrogen in the given compound :

• A. a
• B. b
• C. c
• D. d

Answer 1

The correct option is A a

As we know acidic strength is directly proportional to the electon withdrawing capacity of the group. The electon withdrawing capacity of -NH is less than -C=O.

So, the conjugate base will be stabilised by two electon withdrawing groups and -C=O group has more electon withdrawing capacity and also by resonace. Therefore, $H_a$ will be the most acidic hydrogen.