Question

Identify the statement(s) which are correctly matched:
I. Autosomal disorder: Affects females more than males
II. Mutation in a single gene: Mendelian disorder
III. Chromosomal disorder: change in one gene in a chromosome
IV. Pedigree charts: Knowledge of family history of a genetic disease helps in its construction

Answer 1

Autosomal disorders are the disorders due to single gene mutations occurring on autosomes. They can equally be expressed in males and females. Their expression is not limited to either of the sexes.
Mendelian disorders are genetically inherited disorders which are caused due to mutation in a single gene on a chromosome. They are inherited according to the Mendel's laws of inheritance.
Chromosomal disorders are genetic disorders caused due to changes such as deletion or addition of entire segments of chromosomes.
Pedigree chart is a graphical representation of a family chart
showing the transmission of a particular trait or disease. Knowledge of the family history of the disease helps in creating the chart and also helps in understanding the pattern of transmission of the disease trait and predicting the future possibility of occurrence of the disease.