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Question

Identify whether the following statements are true/false.​
(iii) Process of coagulation starts with the release of a substance from RBCs.​


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Solution

Process of coagulation starts with the release of a substance from platelets.​
The injured tissue cells and platelets disintegrate at the site of injury and release a substance known as thrombokinase or thromboplastin. ​
The thrombokinase acts as an enzyme which converts prothrombin (inactive) of the plasma into thrombin (active), with the help of calcium ions present in the plasma.​
In the presence of calcium ions, the soluble fibrinogen of the plasma is converted to insoluble fibrin by thrombin. ​
This fibrin forms a network of threads at the injury site. ​
Blood cells get trapped in this network of fibrin, the network then squeezes out the rest of the plasma in the form of a clear liquid known as serum. The solid mass left behind is known as a clot.​


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