The correct option is
A P+B−R×Qoption A:
P+B−R×Q
means P is the son of B, who is the husband of R, who is the sister of Q.
means P is the son of B and R and R's sibling is Q
means Q is the maternal uncle of P.
option B
means P is the husband of B, who is the son of R who is the sister of Q
P and B are husband and wife and they have a son R and daughter Q
option C
P+B×R−Q
means P is the son of B, who is the sister of R, who is the husband of Q
R and Q are husband and wife. B is R's sister and P is her son.
option D
P×B−R+Q
means P is the sister of B, who is the husband of R, who is the son of Q.
gives wrong conclusion that B is husband of R who is a male, son of Q.
So, only option A gives the desired relation.