If a molecule was introduced that interfered with the normal function of the enzyme DNA ligase, what would be the most likely effect during replication?

DNA could not unwind for replication to proceed.

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Fragments of DNA could not be joined together.

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New DNA nucleotides could not be added to the growing strand.

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RNA primers could not be replaced with DNA nucleotides.

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Solution

The correct option is B Fragments of DNA could not be joined together.
DNA ligase is an enzyme which is responsible for the ligation of DNA molecules as it catalyzes the formation of a phosphodiester bond between two DNA fragments. This enzyme is both used in the DNA repair and the replication of DNA.
When there is an enzyme that interferes with the normal mechanism of NA ligase the working is affected and the DNA fragments cannot be joined together.

So, the correct option is 'Fragments of DNA could not be joined together.'

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Q. Who discovered that the DNA could be sequenced and the correct series of nucleotides on a fragment of DNA could be identified?

Q. Who discovered that the DNA could be sequenced and the correct series of nucleotide a fragment of DNA could be identified?

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Q. How many of the following statements are correct ?

A. DNA dependent DNA polymerase requires DNA primer for initiating replication but DNA dependent RNA polymerase does not require any primer for transcription.

B. DNA dependent DNA polymerase requires RNA primer for initiating replication but DNA dependent RNA polymerase does not require any primer for transcription.

C. During replication, unwinding of DNA double helix forms a fork-like structure called replication fork.

D. During transcription, unwinding of the DNA double helix by DNA dependent RNA polymerase forms a transcription bubble.

E. During transcription, unwinding of DNA double helix by DNA dependent RNA polymerase forms a transcription fork.

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