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Question

If an antisense strand of DNA in the transcription unit has 3’ ATCTG 5’ sequence, what will be the sequence of nitrogenous bases in the newly synthesized RNA strand?

A
5’ TAGAC 3’
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B
5’ UAGAC 3’
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C
3’ AUCUC 5’
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D
3’ AUGAC 5’
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Solution

The correct option is B 5’ UAGAC 3’
A DNA molecule has two strands, one of which is the sense strand (coding strand) and the other is the antisense strand (template strand).

During the process of transcription, the RNA strand is synthesized on the template DNA strand. Hence, it is complementary to the template DNA strand while usually identical to the coding/sense strand.
Thus the resulting RNA sequence will be 5’ UAGAC 3’.

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