Question

If father had a mutation in his mitochondria and mother was normal. Then in the next generation this mutation will be seen in:

• A. All the offsprings
• B. 50% of the offsprings
• C. One-third of the offsprings
• D. None of the offsprings

Answer 1

The correct option is D None of the offsprings

During fertilisation, mitochondria are contributed by the ovum alone. So, any mutation in the mitochondria (mitochondrial disorders) are inherited from the mother only. Hence, none of the offsprings will be affected here by the mutation.