Question

If for some reason the parietal cells of the gut epithelium become partially nonfunctional, what is likely to happen?

• A. Pancreatic enzymes, especially trypsin and lipase will not work efficiently
• B. Proteins will not be adequately hydrolysed by pepsin to proteoses and peptones
• C. pH of stomach will fall abruptly
• D. Steapsin will not be effective

Answer 1

The correct option is B Proteins will not be adequately hydrolysed by pepsin to proteoses and peptones

Parietal or oxyntic cells secrete HCl which converts pepsinogen to pepsin for facilitating protein digestion. Pepsin converts proteins into proteoses and peptones. If for some reason the parietal cells of the gut epithelium become partially nonfunctional, HCl will not be secreted properly leading to increase in pH of stomach and then proteins will not be adequately hydrolysed by pepsin.