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Question

If haemoglobin is 75% saturated, then how many oxygen molecules are combined with haemoglobin?

A
3
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B
2
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C
3/2
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D
1
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Solution

The correct option is A 3
RBC is a red blood cell which contains haemoglobin protein. Each haemoglobin has 4 globins and 4 heme groups. Each heme group contains iron pigments in it. The oxygen and carbon dioxide alternatively binds to haemoglobin in a reversible manner.

HbReduced haemoglobin(uncombined or deoxygenate haemoglobin)+O2HbO2Oxyhaemoglobin(combined or oxygenated haemoglobin)
Fig. Haemoglobin binds to oxygen to form oxyhaemoglobin.

Oxygen binding to haemoglobin is expressed as percentage.
1 haemoglobin+1 O2 molecule = haemoglobin is 25% saturated
1 haemoglobin+2 O2 molecule = haemoglobin is 50% saturated.
1 haemoglobin+3 O2 molecule = haemoglobin is 75% saturated.
1 haemoglobin+4 O2 molecule = haemoglobin is 100% saturated.

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