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Question

If molecular weight of a polypeptide is 15.3 kDa, what would be the minimum number of nucleotides in the mRNA that codes for this polypeptide? Assume that molecule weight of each amino acid is 90 Da.

A
510
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B
663
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C
123
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D
170
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Solution

The correct option is A 510
As this polypeptide is 15.3kDa in weight, by dividing it with the molecular weight of each amino acid ( 90 Da ) we get 170. It means we have 170 amino acids present in this polypeptide.
Each amino acid is coded by a triplet of codon ( 3 nucleotide sequence ), so 3*170 = 510.
So, the correct option is '510'.

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