Question

If the sequence of bases in the coding strand of a double stranded DNA is 5’-GTTCGAGTC-3’, the sequence of bases in its transcript will be

• A. 5’-GACUCGAAC-3’
• B. 5’-CAAGCUCAG-3’
• C. 5’-GUUCGAGUC-3’
• D. 5’-CUGAGCUUG-3’

Answer 1

The correct option is C 5’-GUUCGAGUC-3’

A template strand is the term that refers to the strand used by DNA polymerase or RNA polymerase to attach complementary bases during DNA replication or RNA transcription, respectively.
Because this new strand is created by complementarity, it matches the opposing strand of DNA, which is called the coding strand. The simple figure below illustrates the process of RNA transcription, in which thymine in the coding strand is replaced by uracil in the growing RNA strand, but all other bases are identical.

So, the correct sequence will be (same as the given sequence except thymine is replaced by uracil):
5’-GUUCGAGUC-3’