Question

If the sequence of bases in the coding strand of a double stranded DNA is $5^{\prime }$ GTTCGAGTC-$3^{\prime }$, the sequence of bases in its transcript will be

• A. $5^{\prime }$-GACUCGAAC-$3^{\prime }$
• B. $5^{\prime }$-CAAGCUCAG-$3^{\prime }$
• C. $5^{\prime }$-GUUCGAGUC-$3^{\prime }$
• D. $5^{\prime }$-CUGAGCUUG-$3^{\prime }$

Answer 1

Answer: (C)

$5^{\prime }$-GUUCGAGUC-$3^{\prime }$

The DNA strand which has same as that of newly synthesized mRNA (transcript) is called as coding strand. The only difference lies in presence of uracil in place of thymine in the transcript. For the given base sequence of coding strand, the transcript sequence will be "5′ -GUUCGAGUC-3′". Thus, the correct answer is option C.