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Question

If there is a deficiency of ADH its effect would be

A
Increase in the volume of urine
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B
Decrease in the volume of urine
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C
The pH of urine will change from 4.8 to 8
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D
Secretion of urochrome takes place
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Solution

The correct option is A Increase in the volume of urine
ADH targets nephrons in kidney to increase water reabsorption and thereby decreasing water content in urine. Inability of neurohypophysial system to produce ADH, causes excess urine production with resultant ion loss from blood. This condition is known as diabetes insipidus (watery urine).
Since ADH regulates the urine volume, not its pH. Urochrome is the yellow pigment, derived from breakdown of heme, which is deposited in blood and then is excreted by kidney with urine.

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