Immune complex-mediated reactions are initiated by antigen-antibody complexes that either is formed locally at the site of tissue damage or deposited there from the circulation. The above-given sentence can be related to
A
Hypersensitivity reaction I
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B
Hypersensitivity reaction II
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C
Hypersensitivity reaction III
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D
Hypersensitivity reaction IV
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Solution
The correct option is D Hypersensitivity reaction III The excess of antigen agglutinates lead to the formation of small immune complexes these when not cleared from the circulation causes Type III hypersensitivity. It involves soluble antigens that are not bound to cell surfaces. When these antigens agglutinate and insert themselves into small blood vessels, joints and glomeruli, cause severe symptoms.