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Question

Immune deficiency disorder, which occurs due to mutation in a gene, involved in the maturation of T and B lymphocytes is ________.

A
IDDM
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B
Hashimoto disease
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C
SCID
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D
Pernicious anemia
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Solution

The correct option is C SCID
  • Insulin-Dependent Diabetes Mellitus or IDDM is an immune deficiency disorder. It occurs due to a mutation in a gene involved in insulin-producing β cells in the pancreas.
  • Hashimoto's disease is an autoimmune disorder that results in hypothyroidism. It results in defects in the maturation of T lymphocytes.
  • Severe combined immunodeficiency (SCID) is an immunodeficiency syndrome. It occurs due to a mutation in the gene involved in the maturation of T and B lymphocytes.
  • Pernicious anemia is also called as vitamin B12 deficiency syndrome. It results due to a lack of intrinsic factor.
Thus, the correct answer is 'Hashimoto disease and SCID.'

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