Question

Immunosuppressive cyclosporin A is obtained from

• A. Aspergillus niger
• B. Penicillium notatum
• C. Monascus purpureus
• D. Trichoderma poplysporum

Answer 1

The correct option is D Trichoderma poplysporum

Cyclosporin is an effective immunosuppressant used in the treatment of autoimmune disorders (such as rheumatoid arthritis) and in organ transplantation to prevent rejection. Cyclosporin lowers the activity of T-cells and hence, suppressing the activity of the immune system. Cyclosporin is isolated from the fungus Trichoderma polysporum. Common side effects include high blood pressure, headache, kidney problems, increased hair growth, and vomiting.

So, the correct answer is 'Trichoderma polysporum'.