Question

Immunosuppressive drugs possess great risk of infection because

• A. These act against specific antigen
• B. These act against all the antigens
• C. These act on antigenic receptors
• D. None of the above

Answer 1

Answer: (D)

None of the above

The immunosuppressive drugs are given to treat individuals with autoimmune disorders and to suppress immunity in order prevent host immune responses against antigens on the transplanted organ, thereby avoiding rejection. There are various kinds of immunosuppressive drugs; some drugs like Calcineurin inhibitors act on some of the immune cells which synthesize the receptors for antigen binding. None of the immunosuppressive drugs acts against antigens. However, use of the immunosuppressive drugs pose a risk of infection because they don't specifically inhibit certain cells that cause autoimmunity or transplant rejection, they inhibit the entire immune system making us vulnerable to infections. Thus, the correct answer is option D.